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Study identifier: NCT06709196 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis

Condition: Cystectomy · Bladder Cancer Requiring Cystectomy · Postoperative Infections  ·  Sponsor: Rigshospitalet, Denmark

PhasePhase 4
Planned participants248
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this trial is to test whether postoperative antibiotics targeted towards bacteria in the urine can reduce the risk of infection after surgical removal of the bladder (cystectomy) compared to a standardised antibiotic prophylaxis. Participants undergoing cystectomy will be randomly assigned to postoperatively receive (A) a standardised orally administered antibiotic prophylaxis currently given at Rigshospitalet, Copenhagen or (B) a conventional orally administered antibiotic prophylaxis targeting bacteria found in the urine postoperatively. The investigators' hypothesis is that the targeted prophylactic antibiotic strategy will reduce the number of infection-related readmissions within 90 days of surgery compared to the standardised prophylaxis.

This description comes directly from the study's public registry record.

Talk to the study team

Maja Vejlgaard  ·  +4535456152  ·  maja.vejlgaard.02@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (5)

Department of Urology, Aalborg University HospitalAalborg, DenmarkNot Yet Recruiting
Department of Urology, Aarhus University HospitalAarhus, DenmarkNot Yet Recruiting
Department of Urology, RigshospitaletCopenhagen, DenmarkRecruiting
Department of Urology, Herlev and Gentofte HospitalHerlev, DenmarkNot Yet Recruiting
Department of Urology, Odense University HospitalOdense, DenmarkNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06709196