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Study identifier: NCT06707662 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Left Septal Pacing or Left Bundle Branch Pacing to Avoid Left Ventricle Systolic Dysfunction

Condition: AV Block  ·  Sponsor: Parc de Salut Mar

PhaseNA
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Right ventricular apical pacing (RVAP) can produce left ventricular dysfunction (LVD). Conduction system pacing (CSP) has been used successfully to reverse LVD in patients with left bundle branch block. A recent randomized controlled trial (RCT) has demonstrated that CSP, mostly performed with left bundle branch area pacing (LBBAP), can preserve normal ventricular function and heart failure admissions compared to RVAP in the setting of a high burden of ventricular pacing11 (Stay Trial). Criteria to assess the LBBAP distinguishes those cases in which the LBB is captured (LBBP) from those in which only the muscular septum surrounding the LBB is captured (LVSP). To date, data regarding LVSP to preserve left ventricle ejection fraction (LVEF) is scarce and limited to non-randomized studies.

This description comes directly from the study's public registry record.

Talk to the study team

Ermengol Valles, PhD  ·  0034666437038  ·  ermengolvalles@mac.com

Jesus Jimenez, MD  ·  0034680714927  ·  jejilo78@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital del Mar - IMIMBarcelona, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06707662