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Study identifier: NCT06707493 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ivosidenib as Post-HSCT Maintenance for AML

Condition: IDH1 Mutation · Acute Myeloid Leukemia (AML) · Hematopoietic Stem Cell Transplant (HSCT)  ·  Sponsor: Massachusetts General Hospital

PhasePhase 2
Planned participants75
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a Phase 2 study of the study drug, ivosidenib (a mutant IDH1 inhibitor), compared to placebo, given to patients with IDH1-mutant acute myeloid leukemia (AML) after hematopoietic stem cell transplantation (HCT).

This description comes directly from the study's public registry record.

Talk to the study team

Amir T Fathi, MD  ·  617-724-1124  ·  afathi@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (6)

Emory University HospitalAtlanta, Georgia, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Ohio State University Wexner Medical Center- James Cancer HospitalColumbus, Ohio, United StatesRecruiting
Huntsman Cancer Institute, University of UtahSalt Lake City, Utah, United StatesRecruiting
Froedtert Hospital & the Medical College of WisconsinMilwaukee, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06707493