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Study identifier: NCT06707233 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Y-90 SIRT for Unresectable HCC Larger Than 7cm

Condition: Hepatocellular Carcinoma Non-Resectable  ·  Sponsor: Second Affiliated Hospital of Guangzhou Medical University

PhasePhase 2
Planned participants33
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a phase II clinical study to evaluate the efficacy and safety of SIRT in patients with HCC greater than 7 cm. After enrollment, patients received yttrium-90 selective internal radiation therapy. The primary endpoint of the study is objective reponse rate (ORR) as assessed by mRECIST. Secondary endpoints were: objective response rate (ORR) as assessed by RECIST 1.1, disease control rate (DCR), progression-free survival (PFS), time to response (TTR), duration of response (DOR), overall survival (OS), and safety (incidence and severity of adverse events).

This description comes directly from the study's public registry record.

Talk to the study team

Mingyue Cai, Dr.  ·  +86-20-34156205  ·  cai020@yeah.net

Kangshun Zhu, Dr.  ·  +86-20-34156205  ·  zhksh010@163.com

Always discuss trial participation with your own doctor first.

Locations (2)

The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06707233