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Study identifier: NCT06704945 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

No Axillary Surgical Treatment in Clinically Lymph Node Negative Patients on Ultrasonography After Neoadjuvant Chemotherapy

Condition: Breast Cancer · Neoadjuvant Therapy · Sentinel Lymph Node Biopsy  ·  Sponsor: Seoul National University Hospital

PhasePhase 3
Planned participants464
Who can joinFemale, 19 Years to no upper limit
Healthy volunteersNo

About this study

NEO-NAUTILUS is a prospective, multicenter, randomized phase III clinical trial to evaluate whether omitting axillary lymph node surgery (ALND or SLNB) in clinically lymph node-negative breast cancer patients after neoadjuvant chemotherapy is non-inferior to performing SLNB in terms of 5-year disease-free survival.

This description comes directly from the study's public registry record.

Talk to the study team

Wonshik Han, MD, PhD.  ·  82-2-3461-6060  ·  hanw@snu.ac.kr

Always discuss trial participation with your own doctor first.

Locations (1)

Seoul National University HopsitalSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT06704945