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Study identifier: NCT06704269 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

Condition: Generalized Myasthenia Gravis  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 1/Phase 2
Planned participants15
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This is a phase I/II study to assess safety, efficacy, and cellular kinetics of YTB323 in participants with treatment-resistant generalized myasthenia gravis. YTB323 is a Biological CAR-T cell therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (11)

Univ Cali Irvine ALS NeuromuscularOrange, California, United StatesRecruiting
Wake Forest Univ School of MedicineWinston-Salem, North Carolina, United StatesRecruiting
Thomas Jefferson UniversityPhiladelphia, Pennsylvania, United StatesRecruiting
Houston Methodist HospitalHouston, Texas, United StatesRecruiting
Novartis Investigative SiteBordeaux, FranceRecruiting
Novartis Investigative SiteBrest, FranceRecruiting
Novartis Investigative SiteLille, FranceRecruiting
Novartis Investigative SiteChiba, Chiba, JapanRecruiting
Novartis Investigative SiteKyoto, JapanRecruiting
Novartis Investigative SiteSheffield, South Yorkshire, United KingdomRecruiting
Novartis Investigative SiteLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06704269