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Study identifier: NCT06703814 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PROtective Ventilation With FLOW-Controlled Ventilation

Condition: Postoperative Pulmonary Complications (PPCs) · Feasibility Studies · Pilot Study  ·  Sponsor: Cantonal Hospital of St. Gallen

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The investigators want to investigate in patients undergoing robot-assisted laparoscopic surgery (a minimally invasive procedure) how applicable flow-controlled ventilation is, and whether it might also be safer than the current ventilation techniques, as well as its impact on potentially reducing the risk of lung-specific complications. Flow-controlled ventilation has already been tested in several studies on animals and humans and has proven to be a safe form of ventilation for patients undergoing surgery under general anesthesia. When patients undergo major surgery, general anesthesia is required and, as a result, mechanical ventilation of the lungs. Especially in long and complex surgeries, ventilation can become more difficult or lead to complications postoperatively. These patients may then experience shortness of breath, coughing, or require medication to improve lung function. In some cases, reintubation or additional mechanical ventilation may be necessary for support. Previous human studies have shown that flow-controlled ventilation is less stressful and, therefore, potentially safer for the lungs compared to traditional ventilation techniques, and that less supplemental oxygen is required. This effect and the safety of flow-controlled ventilation have been demonstrated in several studies. Therefore, in this study, the investigators aim to explore whether flow-controlled ventilation is potentially safer and easier to apply than traditional ventilation technique…

This description comes directly from the study's public registry record.

Talk to the study team

Timur Yurttas, MD  ·  +41714949158  ·  proflow@kssg.ch

Always discuss trial participation with your own doctor first.

Locations (3)

Department of Anaesthesiology, Medical University InnsbruckInnsbruck, Tyrol, AustriaRecruiting
Department of Anesthesiology, Intensive Care and Pain Medicine, BG University Hospital Bergmannsheil, Ruhr-University Bochum, GermanyBochum, Germany, GermanyCompleted
Department of Anaesthesiology, Rescue- and Pain Medicine Cantonal Hospital St. GallenSankt Gallen, Canton of St. Gallen, SwitzerlandCompleted

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Source record: clinicaltrials.gov/study/NCT06703814