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Study identifier: NCT06703073 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

Condition: Acute Respiratory Distress Syndrome (ARDS) · ARDS · ARDS (Acute Respiratory Distress Syndrome)  ·  Sponsor: PPD Development, LP

PhasePhase 2
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 2 multicenter, randomized, double-blinded, placebo-controlled study that will evaluate the safety and efficacy of host-directed therapeutics in hospitalized adults diagnosed with Acute Respiratory Distress Syndrome (ARDS) utilizing a platform trial design. Participants will be randomized to receive either a placebo or one of the active treatments. This record describes the default procedures and analyses for all cohorts. Each specific cohort may have additional eligibility requirements, safety and efficacy procedures, or endpoints, which will be described in the corresponding intervention-specific records on clinicaltrials.gov listed below in the detailed description.

This description comes directly from the study's public registry record.

Talk to the study team

Just Breathe Trial Team  ·  Please email  ·  crgjustbreathealerts.sm@thermofisher.com

Always discuss trial participation with your own doctor first.

Locations (40)

University of Alabama HospitalBirmingham, Alabama, United StatesNot Yet Recruiting
Community Regional Medical CenterFresno, California, United StatesRecruiting
Long Beach Memorial Medical CenterLong Beach, California, United StatesRecruiting
University of California Irvine Medical CenterOrange, California, United StatesRecruiting
University of California Davis Medical Center - Pulmonary MedicineSacramento, California, United StatesRecruiting
Denver Health Hospital and AuthorityDenver, Colorado, United StatesNot Yet Recruiting
MedStar Washington Hospital CenterWashington D.C., District of Columbia, United StatesRecruiting
Nova Clinical ResearchBradenton, Florida, United StatesRecruiting
North Florida / South Georgia Veterans Health SystemGainesville, Florida, United StatesRecruiting
Sarasota Memorial HospitalSarasota, Florida, United StatesRecruiting
St. Luke's Boise Medical CenterBoise, Idaho, United StatesRecruiting
Northshore University Healthsystem Research InstituteEvanston, Illinois, United StatesNot Yet Recruiting

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06703073