Condition: Sickle Cell Disease Vaso-occlusive Crisis · Sponsor: CSL Behring
This is a phase 2, randomized, multiple-dose, placebo-controlled study designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of CSL889 (human hemopexin) when given intravenously (IV) to adults and adolescents with sickle cell disease (SCD) experiencing vaso-occlusive crises (VOC). The main objectives of the study are to evaluate the safety and tolerability of CSL889 in study participants, and to assess how CSL889 affects the time it takes for VOC to resolve in participants with SCD.
This description comes directly from the study's public registry record.
Trial Registration Coordinator · +1 610-878-4697 · clinicaltrials@cslbehring.com
Always discuss trial participation with your own doctor first.
| Univ. of California, San Francisco Health Care | Oakland, California, United States | Recruiting |
| University of California Irvine | Orange, California, United States | Not Yet Recruiting |
| Golisano Children's Hospital | Fort Myers, Florida, United States | Recruiting |
| The Foundation for Sickle Cell Disease | Hollywood, Florida, United States | Recruiting |
| University of Louisville Hospital | Louisville, Kentucky, United States | Recruiting |
| University of Maryland | Baltimore, Maryland, United States | Recruiting |
| Detroit Medical Center | Detroit, Michigan, United States | Recruiting |
| Henry Ford Health System | Detroit, Michigan, United States | Recruiting |
| Mount Sinai Medical Center | New York, New York, United States | Recruiting |
| Jacobi Medical Center | The Bronx, New York, United States | Recruiting |
| East Carolina University | Greenville, North Carolina, United States | Recruiting |
| University of Cincinnati | Cincinnati, Ohio, United States | Recruiting |
+ 7 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06699849