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Study identifier: NCT06699199 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Silver Diamine Fluoride Application on Oral Microbiome of Healthy Pediatric Patient

Condition: Dental Caries  ·  Sponsor: King Abdulaziz University

PhasePhase 4
Planned participants50
Who can joinAll sexes, 4 Years to 12 Years
Healthy volunteersNo

About this study

This clinical trial aims to learn more about the working mechanism of an antimicrobial agent used to manage dental caries, especially in young, uncooperative children. It will also provide a deeper insight into different products of the same agent and its effectiveness in Arresting dental caries. The main questions it aims to answer are: What is the clinical impact of silver diamine fluoride application in caries-active children? What is the antimicrobial effect of silver diamine fluoride in oral microbial inhabitants? Researchers will compare silver diamine fluoride (SDF)only and silver diamine fluoride+ potassium iodide(SDF+KI) to see which materials substantially affect on dental caries and oral microbial inhabitants Participants/Parent will: The parent will fill out a comprehensive data sheet for the child (childhood and current dental and medical history) Visit the dental clinic to Receive one of 2 (SDF or SDF+KI) treatment applications once Visit the clinic a 2nd time for a 2-4 week Treatment Follow-up Go through the sample collection process twice( pre- and 2-4 weeks post- Treatment) Sample collection including (Saliva- Biofilm and caries tissue sample)

This description comes directly from the study's public registry record.

Talk to the study team

Dr.Doaa Y Jamal, BDS, MSc, SBPD  ·  (+966)-558887632  ·  Djamal0004@stu.kau.edu.sa

Prof. (Dr.) Abdullah S AlMushayt, BDS, MSc, PhD  ·  (+966)-507733313  ·  aalmushayt@kau.edu.sa

Always discuss trial participation with your own doctor first.

Locations (1)

University Dental hospital of King Abdulaziz UniversityJeddah, Mecca Region, Saudi ArabiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06699199