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Study identifier: NCT06698458 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

Condition: Pancreatic Cancer · Pancreatic Adenocarcinoma · Metastatic Pancreatic Cancer  ·  Sponsor: Alpha Tau Medical LTD.

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to 120 Years
Healthy volunteersNo

About this study

This is a multi-center clinical study enrolling up to 30 participants (15 patients in each cohort). The primary objective of the study is to evaluate the safety of Alpha DaRT in combination with chemotherapy, based on the cumulative incidence rate, severity and outcome of device related AEs. Classification of AEs will be done according to CTCAE V5. The secondary objectives of the study are to: * Assess efficacy of the Alpha DaRT sources in combination with chemotherapy, determined by overall and progression-free survival. * Assess pain control * Assess rate of surgical resection in Cohort 1.

This description comes directly from the study's public registry record.

Talk to the study team

Liron Dimnik  ·  +972-2-3737-7000  ·  LironD@alphatau.com

Always discuss trial participation with your own doctor first.

Locations (15)

Banner MD Anderson Cancer CenterGilbert, Arizona, United StatesRecruiting
City of HopeGoodyear, Arizona, United StatesNot Yet Recruiting
Honor HealthScottsdale, Arizona, United StatesRecruiting
Cedars-SinaiLos Angeles, California, United StatesNot Yet Recruiting
Advent Health Cancer InstituteOrlando, Florida, United StatesNot Yet Recruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Bassett Healthcare NetworkCooperstown, New York, United StatesRecruiting
NYU Langone HealthNew York, New York, United StatesRecruiting
Lenox hill HospitalNew York, New York, United StatesNot Yet Recruiting
Montefiore Medical CenterThe Bronx, New York, United StatesRecruiting
Texas OncologyHouston, Texas, United StatesNot Yet Recruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06698458