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Study identifier: NCT06698250 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

Condition: Hepatocellular Carcinoma  ·  Sponsor: Anwaar Saeed

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will investigate if modulating the tumor microenvironment with biologic agents like XL-092 will have synergistic effect when combined with checkpoint based immunotherapeutic treatment of patients with hepatocellular carcinoma (HCC).

This description comes directly from the study's public registry record.

Talk to the study team

Debra Diecks  ·  4126238364  ·  diecksda@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (3)

UPMC Hillman Cancer CenterPittsburgh, Pennsylvania, United StatesRecruiting
Houston Methodist Neal Cancer CenterHouston, Texas, United StatesNot Yet Recruiting
Mays Cancer Center, UT Health San AntonioSan Antonio, Texas, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06698250