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Study identifier: NCT06698159 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Wide-Antral Pulmonary Vein Isolation in Atrial Fibrillation Ablation with a Single-shot Technique (WIDER-PVI)

Condition: Atrial Fibrillation · Atrial Fibrillation (Paroxysmal)  ·  Sponsor: Hospital Universitario 12 de Octubre

PhaseNA
Planned participants440
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The WIDER PVI study is a multicentre randomized clinical trial to compare the efficacy of antral versus extended antral PVI in patients with paroxysmal or persistent AF undergoing this procedure using a cryoablation balloon capable of 28 mm diameter (antral isolation) or 31 mm diameter (extended antral isolation) applications. The aim is to evaluate an objective of superiority of the extended antral isolation strategy versus antral isolation in the recurrence of atrial tachyarrhythmias at 1-year follow-up, both in episodes of \>30 seconds duration and in overall arrhythmic load.

This description comes directly from the study's public registry record.

Talk to the study team

Daniel Rodríguez Muñoz, MD PhD  ·  659385591  ·  daniel.rodriguez.mnz@gmail.com

Always discuss trial participation with your own doctor first.

Locations (17)

IRCCS Neuromed Mediterranean Neurological InstitutePozzilli, Isernia, ItalyNot Yet Recruiting
Casa di cura Villa dei FioriAcerra, Napoli, ItalyNot Yet Recruiting
Poliambulanza Institute Hospital FoundationBrescia, ItalyNot Yet Recruiting
Ospedale Santa Maria GorettiLatina, ItalyNot Yet Recruiting
Clinica San MicheleMaddaloni, ItalyNot Yet Recruiting
Fondazione IRCCS San Gerardo dei TintoriMonza, ItalyNot Yet Recruiting
Pellegrini HospitalNaples, ItalyNot Yet Recruiting
Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of PadovaPadova, ItalyNot Yet Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, University "Cattolica del Sacro Cuore"Rome, ItalyNot Yet Recruiting
S. Pietro Fatebenefratelli HospitalRome, ItalyNot Yet Recruiting
HU BasurtoBilbao, SpainNot Yet Recruiting
HU Virgen de las NievesGranada, SpainNot Yet Recruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06698159