Condition: Healthy Volunteers · Inflammatory Bowel Disease (IBD) · Sponsor: Region Skane
The diet is assumed to contribute to many of our present non-communicable diseases. Vegetarian products are instead considered to be health promoting, However, it is not verified that the modern vegetarian and vegan products are healthier than the ones they are meant to replace. Products based on vegetables are nowadays often produced with advanced techniques and can therefore differ substantially from the original vegetables. The epithelium in the gut is protected by a mucus layer that efficiently prevents bacteria to encounter the epithelium and even to translocate into the gut and the blood stream. In several inflammatory conditions such as e.g., inflammatory bowel disease (IBD) the barrier integrity is disrupted, and translocation will occur. Fibers are important for the gut microbiota enabling the production of short chain fatty acids (SCFA) that is necessary as nutrition for the epithelial cells, Fibers also promote the development of mucus. The aim of the present study is to evaluate components in the diet that is claimed to be health promoting even though they sometimes can be a hazard to your health. Both fibers and antinutrients can be found in these dietary regimens. The health effects of these products will be studied by analysis of the gut microbiota and the barrier integrity as markers of the health status. Gut microbiota will be analyzed with next generation sequencing and q-PCR (polymerase chain reaction). Diversity and the occurrence of different species wi…
This description comes directly from the study's public registry record.
Klas Sjöberg, Adj prof · +46 40 33 61 61 · klas.sjoberg@med.lu.se
Åsa Håkansson, Associate prof · +46 46 222 83 26 · asa.hakansson@ple.lth.se
Always discuss trial participation with your own doctor first.
| Dept of Gastroenterology | Malmö, Sweden | Recruiting |
| Dept of Gastroenterology | Malmö, Sweden | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06696222