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Study identifier: NCT06695845 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Condition: Breast Cancer · Gastric Cancer · Esophageal Cancer  ·  Sponsor: Jazz Pharmaceuticals

PhasePhase 2
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of zanidatamab for the treatment of participants with previously treated solid tumors that have Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ overexpression.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trial Disclosure & Transparency  ·  215-832-3750  ·  ClinicalTrialDisclosure@JazzPharma.com

Always discuss trial participation with your own doctor first.

Locations (28)

Arizona Oncology Associates, PC - NAHOAPrescott, Arizona, United StatesWithdrawn
Rocky Mountain Cancer CenterLittleton, Colorado, United StatesRecruiting
Florida Cancer Specialists - SouthFort Myers, Florida, United StatesWithdrawn
Florida Cancer Specialists - Lake NonaOrlando, Florida, United StatesActive Not Recruiting
Florida Cancer Specialists - NorthSt. Petersburg, Florida, United StatesWithdrawn
Florida Cancer Specialists - EastWest Palm Beach, Florida, United StatesWithdrawn
Affiliated OncologistsChicago Ridge, Illinois, United StatesWithdrawn
Barbara Ann Karmanos Cancer InstituteDetroit, Michigan, United StatesWithdrawn
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Alliance Cancer SpecialistsHorsham, Pennsylvania, United StatesWithdrawn
Tennessee Cancer SpecialistsKnoxville, Tennessee, United StatesWithdrawn
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06695845