Condition: Post-aggressive Immunosuppression · Adult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6 · Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C · Sponsor: Assistance Publique - Hôpitaux de Paris
The vast majority of serious clinical situations leading to intensive care (septic shock, polytrauma, acute cerebral aggression, major surgery) are characterized by significant systemic inflammation. Recently, the existence of a common immune response pattern to acute aggression has been demonstrated, and with it the existence of a phenomenon known as post-aggressive immunosuppression (PAIS).
This description comes directly from the study's public registry record.
Charles De ROQUETAILLADE, MD · 01 49 95 55 68 · charles.de-roquetaillade@aphp.fr
Benjamin CHOUSTERMAN, Professor · 01 49 95 85 18 · benjamin.chousterman@aphp.fr
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| Dr de Roquetaillade | Paris, France | Recruiting |
| Pr Dépret | Paris, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06694740