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Study identifier: NCT06694259 Synced from ClinicalTrials.gov · July 29, 2026
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Comparison of Anatomical and Functional Outcomes of Laser Photocoagulation and Cryopexy in Patients with Rhegmatogenous Retinal Detachment Treated with Pneumatic Retinopexy

Condition: Rhegmatogenous Retinal Detachment  ·  Sponsor: Clinical Hospital Center, Split

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Rhegmatogenous Retinal Detachment is a pathological condition in which the inner layers of the retina separate from its outermost layer due to fluid entering between these layers through a retinal tear. Retinal detachment is one of the most urgent conditions in ophthalmology; if left untreated, it leads to severe vision loss and blindness. The only possible treatment is a surgical procedure to close the tear and reattach the separated retinal layers. Currently, three techniques are used for surgically managing retinal detachment with a tear. You will undergo a technique called pneumatic retinopexy. In this procedure, reattachment of the retina is achieved by injecting sulfur hexafluoride gas (SF6) into the vitreous (the gel that fills the eye) about 4 millimeters from the corneal edge, using a very fine needle. The retinal tear is then closed by either freezing (cryotherapy) immediately before the gas injection or by laser photocoagulation after the gas is introduced. The procedure will be done under local anesthesia, with the pupil first dilated using eye drops. After the procedure, a combination of antibiotics and corticosteroids will be instilled in the eye, followed by an ointment of the same combination, and the eye will be covered with a sterile dressing. You will need to maintain a specific head position, depending on the location of the retinal tear, for several days while the gas is present in the eye. This position helps the gas press against the tear, allowing it…

This description comes directly from the study's public registry record.

Talk to the study team

Ivan Borjan, MD  ·  +385981715350  ·  ivan.borjan@kbsplit.hr

Ljubo Znaor, prof.  ·  lznaor@kbsplit.hr

Always discuss trial participation with your own doctor first.

Locations (1)

Clinical Hospital Center, SplitSplit, CroatiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06694259