Condition: Cardiogenic Shock · Sponsor: University Hospital, Strasbourg, France
Cardiogenic shock (CS) is characterized by tissue hypoperfusion resulting from cardiac dysfunction, without hypovolemia, where the ventricular pump is unable to generate adequate blood flow to meet the metabolic needs of the organs. To date, the management of CS is a challenge for cardiologists and intensive care physicians, particularly with regard to the stratification of the severity of these patients to accurately determine the prognostic outcome. Thus, although specific prognostic scores for CS already exist, they are often inefficient and difficult to calculate quickly at the patient's bedside. For example, the CardShock risk score is a score composed of seven variables (including biological and echocardiographic parameters) allowing in the best case to obtain an area under the curve (AUC) for the prediction of mortality around 0.7. More recently, the SCAI Shock classification was developed to progressively stratify patients into five groups of increasing severity, ranging from A to E for the most serious. Although its prognostic interest is better than the CardShock, this recently updated classification is also based on biological or echocardiographic parameters that are sometimes difficult to collect in an emergency. Thus, there is currently no simple and optimal prognostic score to predict the prognosis of patients and even less of a score that takes into account the overall clinical fragility of patients appropriately. In this context, the Rockwood clinical fragi…
This description comes directly from the study's public registry record.
Hamid MERDJI, MD · 33 3 69 55 11 23 · hamid.merdji@chru-strasbourg.fr
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| Service de Médecine Intensive - Réanimation - CHU de Strasbourg - France | Strasbourg, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06692855