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Study identifier: NCT06692192 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The RECAP2 Study: Midazolam and Psilocybin

Condition: Psilocybin  ·  Sponsor: University of Wisconsin, Madison

PhasePhase 1
Planned participants60
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to learn about the role that inducing neuroplasticity (the brain's ability to adapt and change) plays in the behavioral effects of psilocybin in people who have experienced a mild decline in emotional wellbeing. Researchers will compare different doses of psilocybin combined with midazolam or placebo to see what dose induces increased wellbeing. Participants will: * Receive one of four possible combinations of medications * Undergo an MRI * Complete questionnaires * Undergo transcranial magnetic stimulation (TMS) and EEG

This description comes directly from the study's public registry record.

Talk to the study team

RECAP Study Contact  ·  608-263-4852  ·  recap2@psychiatry.wisc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UW School of Medicine and Public HealthMadison, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06692192