← Eichor
Study identifier: NCT06691230 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PeRfusiOn Post tHrombEcTomy (PROPHET)

Condition: Stroke, Acute, Ischemic  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhaseN/A
Planned participants279
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Endovascular mechanical thrombectomy is the standard of care for treating patients with a large-vessel occlusion acute ischemic stroke. However, in more than half of these patients, remaining distal vessel occlusions limit the benefit of this therapy. Currently the detection of residual vessel occlusions and the decision for further treatment by the operator is based on the 2D digital subtraction angiography (DSA) images. However, this technique has several limitations. Recently, a new imaging technique, with the possibility to acquire 3D time-resolved perfusion images directly in the operating room was introduced (the flat-panel detector computed tomography perfusion imaging, FDCTP). It can overcome the spatial limitations of 2D DSA, but the details on clinical validation and utility of FDCTP are currently lacking.

This description comes directly from the study's public registry record.

Talk to the study team

Johannes Kaesmacher, Prof.  ·  +41 31 66 4 05 38  ·  nctu@insel.ch

Seraina Beyeler, PhD  ·  +41 31 632 39 70  ·  seraina.beyeler@insel.ch

Always discuss trial participation with your own doctor first.

Locations (2)

University Hospital BaselBasel, SwitzerlandNot Yet Recruiting
University Hospital BernBern, SwitzerlandRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06691230