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Study identifier: NCT06690840 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer Patients

Condition: Triple Negative Breast Cancer  ·  Sponsor: European Institute of Oncology

PhasePhase 2
Planned participants45
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Triple-negative breast cancer (TNBC) is among the most aggressive and lethal types of breast cancer, and currently available therapies have an unsatisfactory impact on patients' survival. The primary aim of this clinical trial is to evaluate efficacy in terms of Overall Response Rate (ORR) of atezolizumab plus cyclophosphamide and vinorelbine in first line patients with unresectable locally advanced or metastatic TNBC patients, previously treated with anti-programmed cell death ligand-1 (PD-L1) or anti-programmed cell death-1 (PD-1) - containing regimens, in the neoadjuvant/adjuvant setting.

This description comes directly from the study's public registry record.

Talk to the study team

Elisabetta Munzone, MD  ·  +39 0257489405  ·  elisabetta.munzone@ieo.it

Mara Negri  ·  +39 0257489536  ·  mara.negri@ieo.it

Always discuss trial participation with your own doctor first.

Locations (5)

Fondazione IRCCS San Gerardo Dei TintoriMonza, Monza, ItalyRecruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCSRoma, Roma, ItalyNot Yet Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCSRoma, Roma, ItalyNot Yet Recruiting
Azienda Sanitaria Locale BrBrindisi, ItalyNot Yet Recruiting
European Institute of OncologyMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06690840