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Study identifier: NCT06689085 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

Condition: Hypogonadism, Male  ·  Sponsor: Halozyme Therapeutics

PhasePhase 3
Planned participants100
Who can joinMale, 12 Years to 17 Years
Healthy volunteersNo

About this study

This is a 52-week open label single arm study + 24-Month long-term safety extension to investigate the effects of XYOSTED, as testosterone replacement therapy, on adolescent males with either primary or secondary hypogonadism. The study aims to determine the effectiveness of XYOSTED measured by continuation or induction of puberty in addition to XYOSTED dosage, safety and testosterone levels.

This description comes directly from the study's public registry record.

Talk to the study team

Director Clinical Operations, MPH, CPM  ·  609-331-1670  ·  jbitsura@halozyme.com

Chief Medical Officer, MD, PhD  ·  858-344-9400  ·  ctheuer@halozyme.com

Always discuss trial participation with your own doctor first.

Locations (20)

Children's Hospital Los AngelesLos Angeles, California, United StatesRecruiting
Rady Children's Hospital - San DiegoSan Diego, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
Nemours Children's Specialty Care - JacksonvilleJacksonville, Florida, United StatesRecruiting
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesRecruiting
Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting
University of Massachusetts Memorial Medical CenterWorcester, Massachusetts, United StatesRecruiting
M Health Fairview U MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Washington University School of Medicine in St. LouisSt Louis, Missouri, United StatesRecruiting
The DOCSLas Vegas, Nevada, United StatesRecruiting
Children's Hospital at MontefioreThe Bronx, New York, United StatesRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06689085