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Study identifier: NCT06687941 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

Condition: Neoplasms · Carcinoma, Hepatocellular · Carcinoma, Non-Small-Cell Lung  ·  Sponsor: Aptamer Sciences, Inc.

PhasePhase 1
Planned participants70
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

This is the first in human trial clinical study of AST-201 in patients with GPC3-positive advanced solid tumors. This study aims to evaluate the safety, tolerability, pharmacokinetic properties, and preliminary efficacy of AST-201 across various tumor types.

This description comes directly from the study's public registry record.

Talk to the study team

Aptamer Sciences Inc.  ·  +82-70-5067-4275  ·  kjkim@aptsci.com

Always discuss trial participation with your own doctor first.

Locations (4)

National Cancer Center, KoreaGoyang-si, Gyeonggi-do, South KoreaRecruiting
CHA Bundang Medical CenterSeongnam, South KoreaRecruiting
Severance HospitalSeoul, South KoreaRecruiting
Samsung Medical CenterSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT06687941