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Study identifier: NCT06687733 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety and Efficacy Study of NGGT002 in cPKU Adult Subjects

Condition: Phenylketonurias  ·  Sponsor: NGGT (Suzhou) Biotechnology Co., Ltd.

PhasePhase 1/Phase 2
Planned participants18
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

This is a Phase 1/2, open-label, multiple-center, dose escalation and cohort expansion study to evaluate the safety and efficacy of NGGT002 in adult subjects with classic Phenylketonuria (PKU). NGGT002 is a rAAV8 based vector carrying a functional copy of the human PAH gene. Participants will receive a single administration of NGGT002 and will be followed for safety and efficacy for 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Huan Zhou, PhD  ·  8613665527160  ·  zhouhuanbest@vip.163.com

Always discuss trial participation with your own doctor first.

Locations (2)

First Affiliated Hospital of Bengbu Medical CollegeBengbu, Anhui, ChinaRecruiting
Xinhua Hospital Affifiated to Shanghai Jiao Tong University School of MedicineShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06687733