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Study identifier: NCT06687603 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

Condition: Barrett Esophagus · Gastroesophageal Reflux · Esophageal Adenocarcinoma  ·  Sponsor: Case Comprehensive Cancer Center

PhaseNA
Planned participants800
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical trial is to develop a method to detect Barrett's esophagus in individuals with a new office based diagnostic test. Barrett's esophagus is a condition in which the flat pink lining of the swallowing tube that connects the mouth to the stomach (the esophagus) becomes damaged by acid reflux. The main question it aims to answer is: Can this approach demonstrate efficacy for screening of Barrett's esophagus? Participants will: * Participate in a questionnaire. * Undergo a capsule balloon test, called EsoCheck. * Have their EsoCheck sample sent to the laboratory for an EsoGuard test, which is used to detect Barrett's esophagus. * Participants will undergo upper endoscopy as part of standard of care.

This description comes directly from the study's public registry record.

Talk to the study team

Wendy Brock  ·  216-844-3853  ·  Wendy.brock@uhhospitals.org

Always discuss trial participation with your own doctor first.

Locations (5)

University of ColoradoAurora, Colorado, United StatesRecruiting
Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting
University of North Carolina at Chapel HillChapel Hill, North Carolina, United StatesRecruiting
University Hospitals Cleveland Medical CenterCleveland, Ohio, United StatesRecruiting
Cleveland Clinic Taussig Cancer CenterCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06687603