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Study identifier: NCT06687057 Synced from ClinicalTrials.gov · July 29, 2026
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A Heart Rate Variability (HRV) Biofeedback Training in Functional Gastrointestinal Disorders (FGID)

Condition: Functional Gastrointestinal Disorders (FGIDs)  ·  Sponsor: Fondazione Don Carlo Gnocchi ETS

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Functional Gastrointestinal Disorders (FGIDs) are conditions characterized by chronic gastrointestinal symptoms without evidence of pathology. These disorders are believed to result from alterations in gut-brain communication. The most common subtypes are Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD), often accompanied by chronic pain, anxiety, and depression. The role of stress in the manifestation of FGIDs is notable, with stress-related distress affecting the nerve pathways that connect gut and brain. Recent interest has focused on the use of Heart Rate Biofeedback (HRV). High levels of stress are associated with reduced HRV, which is common in patients with FGID. HRV biofeedback has been shown to be effective in improving parasympathetic tone and reducing sympathetic tone. The present study aims to evaluate the effectiveness of this approach in reducing stress and symptoms associated with FGIDs in college students. The project involves online screening to recruit participants, who will then be randomized to receive either the true HRV biofeedback treatment or a placebo condition. Pre- and post-treatment assessments include psychological questionnaires, physiological recordings, and a three-month follow-up. The treatment is expected to improve HRV, thereby reducing anxiety and gastrointestinal symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Eleonora Volpato, PsyD, PhD  ·  3293782692  ·  eleonora.volpato@unicatt.it

Elisabetta Patron, PsyD, PhD  ·  elisabetta.patron@unipd.it

Always discuss trial participation with your own doctor first.

Locations (1)

Eleonora VolpatoMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06687057