Condition: Neuroblastoma · Sponsor: The General Hospital of Western Theater Command
Neuroblastoma (NB) is a malignant tumor of the sympathetic nervous system.Chemotherapy and autologous hematopoietic stem cell transplantation are the main treatments for neuroblastoma, and the prognosis of patients with high-risk recurrence and refractory treatment is very poor. There is a large unmet medical need in patients with relapsed refractory neuroblastoma, and further research into new therapeutic approaches is needed for these patients.GD2 is a dissialic ganglioside expressed by neuroectodermal tumors. The proportion of GD2 expression in neuroblastoma is up to 100%, so GD2 is a specific target for neuroblastoma immunotherapy and an ideal target for CAR-T treatment of neuroblastoma.
This description comes directly from the study's public registry record.
JunXia Wang, Ph.D · 0086-28-86571605 · lzwjxyy@163.com
Hai Yi, Ph.D · 0086-28-86571279 · yihaimail@163.com
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| The General Hospital of Western Theater Command | Chengdu, Sichuan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06684639