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Study identifier: NCT06684119 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)

Condition: Pediatric Acute Respiratory Distress Syndrome  ·  Sponsor: Children's Hospital Los Angeles

PhaseNA
Planned participants60
Who can joinAll sexes, 0 Years to 18 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced. The primary and secondary aims of the study are as follows: Identify the difference between the optimal PEEP recommended by EIT metrics and the current guideline recommended approach to identifying optimal PEEP in PARDS. There will be a statistically significant difference in the recommended optimal PEEP identified using the EIT PEEP titration tool and that of the PEEP/FiO2 grid recommendations. Determine the difference in physiologic metrics between EIT optimal PEEP and the PEEP/FiO2 recommended PEEP. Participants will undergoing EIT monitoring while being subjected to PEEP titration protocol.

This description comes directly from the study's public registry record.

Talk to the study team

Hayden Leeds, MD  ·  3233617939  ·  hleeds@chla.usc.edu

Anoopindar Bhalla, MD  ·  323-361-7939  ·  abhalla@chla.usc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Children's Hospital Los AngelesLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06684119