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Study identifier: NCT06683365 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

Condition: Multiple System Atrophy · Parkinsons Disease  ·  Sponsor: Craig van Horne, MD, PhD

PhasePhase 1
Planned participants7
Who can joinAll sexes, 40 Years to 75 Years
Healthy volunteersNo

About this study

This phase I double-blind study focuses on the safety and feasibility of implanting autologous peripheral nerve tissue (PNT) into the substantia nigra area of the brain in persons who have been diagnosed with either Parkinson's disease (PD) or Multiple System Atrophy (MSA). 7 participants will be enrolled, with 4 participants receiving the graft and 3 receiving a sham surgery. Eligible participants will be early in their diagnosis with a lower burden of symptoms. Participants will be followed initially for one year after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Jaimie Hixson  ·  859-323-1908  ·  jaimie.henderson@uky.edu

Group Monitored Email  ·  nervegraft@uky.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of KentuckyLexington, Kentucky, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06683365