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Study identifier: NCT06681844 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Predict Tooth Wear

Condition: Prediction of Tooth Wear  ·  Sponsor: Hospices Civils de Lyon

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Tooth wear, resulting from gradual loss of dental hard tissue due to mechanical and chemical factors, impacts tooth structure, texture, and function. It affects quality of life, with varying prevalence (26.9% to 90.0%), and is traditionally detected visually during check-ups, often at advanced stages. Monitoring alterations in tooth shape via intraoral scanners aids early detection, but restoration remains challenging. Prevention through early detection is vital, as patients may not fully comprehend tooth structure loss until visible. Recently, statistical shape analysis (SSA) used to learn the tooth anatomy and define a reference shape (biogeneric tooth) using. However, assuring landmark consistency is challenging mostly due to biases of the operator. Recently, a robust method called MEG-IsoQuad offered automated, isotopological remeshing. Combining this with SSA holds promise for diagnostic and simulation purposes. This study aims to assess the reliability of a remeshing-SSA approach for altered and intact premolar analysis and compare machine learning algorithms for simulating the shape of the initially intact tooth or future altered one. The clinical perspective of the current work offers possibilities to: * Prevent future tooth wear by detecting it at an early stage; and communicate better to the patient by presenting him/her potential future altered teeth * Simulate the adapted reconstruction for the altered tooth by simulating the initially intact one

This description comes directly from the study's public registry record.

Talk to the study team

Raphael Richet, Clinical Assistant  ·  +33669523314  ·  raphael.richert@univ-lyon1.fr

Maxime Ducret, Professor  ·  maxime.ducret@univ-lyon1.fr

Always discuss trial participation with your own doctor first.

Locations (5)

Indiana University HospitalIndianapolis, Indiana, United StatesRecruiting
KU Leuven University HospitalLeuven, BelgiumRecruiting
Lyon Dental HospitalLyon, FranceRecruiting
King George Medical UniversityLucknow, IndiaRecruiting
Tel Aviv UniversiTel Aviv, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT06681844