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Study identifier: NCT06679140 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Condition: COVID-19 SARS-CoV-2 Infection  ·  Sponsor: Pfizer

PhasePhase 3
Planned participants2330
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease. Eligible participants will be randomly assigned (by chance) to receive ibuzatrelvir or matching placebo orally for 5 days. Co-administration of locally available standard of care is allowed. The total duration of the study is around 6 months.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (248)

Applied Research Center of ArkansasLittle Rock, Arkansas, United StatesRecruiting
National Institute of Clinical Research - BakersfieldBakersfield, California, United StatesRecruiting
Velocity Clinical Research, Huntington ParkHuntington Park, California, United StatesRecruiting
310 Clinical ResearchInglewood, California, United StatesRecruiting
Long Beach Research InstituteLong Beach, California, United StatesRecruiting
Long Beach Clinical TrialsLong Beach, California, United StatesRecruiting
Pacific Clinical Studies Inc.Los Alamitos, California, United StatesRecruiting
Downtown L.A. Research Center, Inc.Los Angeles, California, United StatesRecruiting
Clinica mi Salud by Focil MedOxnard, California, United StatesRecruiting
FOMAT Medical ResearchOxnard, California, United StatesRecruiting
Paradigm Clinical Research, LLCRedding, California, United StatesRecruiting
Acclaim Clinical ResearchSan Diego, California, United StatesRecruiting

+ 236 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06679140