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Study identifier: NCT06678100 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Swallowing Impairments in Adults With and Without Alzheimer's Disease

Condition: Alzheimer Disease · Caregiver Burden · Healthy Aging  ·  Sponsor: Vanderbilt University Medical Center

PhaseN/A
Planned participants240
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersYes

About this study

This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throughout the disease course in people with AD. The overall objective of this study is to evaluate swallowing function in adults with and without Alzheimer's disease. The investigator will also be involving the primary caregivers of individuals with Alzheimer's that are enrolled in the study to better understand the impact of swallowing impairments on the primary caregivers of those with Alzheimer's Disease. Healthy adults and individuals with Alzheimer's disease will: * undergo tests of cough and swallow function * undergo tests of grip and tongue strength * complete questionnaires Caregivers of individuals with Alzheimer's disease will also complete questionnaires.

This description comes directly from the study's public registry record.

Talk to the study team

Cara Donohue, PhD CCC-SLP  ·  615-852-5085  ·  cara.donohue@vumc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06678100