Condition: Adnexal Torsion · Sponsor: Central Hospital, Nancy, France
Adnexal torsion is the rotation of the ovary around its vascular axis resulting, in the absence of treatment, ischemia that can lead to peritonitis by necrosis or impaired fertility. It is a gynecological emergency affecting 3% of women of childbearing age, including from adolescence, and requires surgical treatment as soon as possible, classically within 6 hours. The symptomatology of adnexal torsion is dominated by pelvic pain of sudden onset and variable intensity, an aspecific sign that does not allow a diagnosis of certainty. There are no biological markers and, in the context of the emergency, the only imaging examination available is pelvic ultrasound associated with a Doppler flow analysis but with a low and variable diagnostic performance depending on the studies (sensitivity variable from 46 to 73%). There are currently no tests that can provide a diagnosis of certainty. Only surgical exploration, carried out at the discretion of the practitioner on the basis of a bundle of arguments, can confirm or refute the diagnosis. However, this management strategy leads to the realization of emergency surgical interventions wrongly since 3 out of 10 women will finally not have an adnexal torsion (PMSI data from participating centers: 30 to 45% false positives). Contrast ultrasound is a technique that uses a strict intravascular product to assess the vascularization of the ovary and offers a high diagnostic performance in the context of adnexal torsion. Indeed, a retrospect…
This description comes directly from the study's public registry record.
Charline BERTHOLDT, Pr · +33 383 344 312 · c.bertholdt@chru-nancy.fr
Dorine MANHERTZ, MSc · d.manhertz@chru-nancy.fr
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| CHU | Besançon, France | Not Yet Recruiting |
| CHU | Dijon, France | Not Yet Recruiting |
| CHRU Nancy - Maternité Régionale | Nancy, France | Recruiting |
| CHU | Reims, France | Not Yet Recruiting |
| CMCO | Schiltigheim, France | Not Yet Recruiting |
| CHU Hautepierre | Strasbourg, France | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06677554