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Study identifier: NCT06677229 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury

Condition: Acute Spinal Cord Injury (SCI)  ·  Sponsor: Technophage, SA

PhasePhase 1/Phase 2
Planned participants28
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Technophage identified a promising compound, Eletriptan hydrobromide, that intends to use as a repurposed drug, for the treatment of acute spinal cord injury (SCI) in human subjects. Eletriptan hydrobromide is a well characterized molecule, that has been clinically available for over two decades for the treatment of migraines. It presents a good and manageable safety profile, including for the regimen selected for this trial, and it is generally well tolerated, with minimal side effects. This is an important consideration to have when using repurposed drugs for the treatment of other indications. Technophage believes that the preclinical data collected, in combination with the acceptable safety profile of Eletriptan hydrobromide, support its use as a repurposed drug for the treatment of SCI in humans.

This description comes directly from the study's public registry record.

Talk to the study team

Sofia Corte-Real  ·  +351 215943993  ·  scortereal@technophage.pt

Margarida Barreto  ·  +351 215943993  ·  mbarreto@technophage.pt

Always discuss trial participation with your own doctor first.

Locations (2)

Hospital Universitario Reina SofiaCórdoba, SpainRecruiting
Hospital Universitario La PazMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06677229