Condition: Myelofibrosis · Sponsor: Peking University People's Hospital
Myelofibrosis (MF) is a myeloproliferative neoplasm causing bone marrow failure and high risk of leukemia transformation. JAK2 inhibitors improve symptoms but do not cure MF. Allogeneic stem cell transplantation (allo-HSCT) is the only potential cure, though limited donor availability restricts access. Haploidentical transplantation shows promise but associated with higher graft failure and treatment related mortality. We recently developed a novel regimen of haplo-SCT for MF. This study aims to investigate this novel protocol in a prospective trial to improve MF outcomes.
This description comes directly from the study's public registry record.
Sun Yuqian · 861088326666 · sunyuqian83@hotmail.com
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| Peking University People's Hospital | Beijing, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06674382