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Study identifier: NCT06673095 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

Condition: Clinical Stage IA Cutaneous Melanoma AJCC v8 · Clinical Stage IB Cutaneous Melanoma AJCC v8  ·  Sponsor: OHSU Knight Cancer Institute

PhaseNA
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial compares the effect of a narrow surgical excision (removal) to a wide excision for the treatment of adults with invasive cutaneous melanoma. Currently the standard of care is to take wide margins (boarder of healthy tissue surrounding the melanoma) when removing melanoma. Narrow margin excision removes a smaller amount of healthy tissue when surgically removing the melanoma. Narrow margin excision may be effective in removing the melanoma while also reducing surgical complications and improving quality of life for adults with invasive cutaneous melanoma.

This description comes directly from the study's public registry record.

Talk to the study team

Paige Smith  ·  503-418-4268  ·  smitpaig@ohsu.edu

Always discuss trial participation with your own doctor first.

Locations (5)

University of California, DavisDavis, California, United StatesNot Yet Recruiting
University of Kentucky/Markey Cancer CenterLexington, Kentucky, United StatesNot Yet Recruiting
University of MichiganAnn Arbor, Michigan, United StatesNot Yet Recruiting
University Hospitals Cleveland Medical CenterCleveland, Ohio, United StatesNot Yet Recruiting
OHSU Knight Cancer InstitutePortland, Oregon, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06673095