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Study identifier: NCT06672822 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intralesional Injection of STS in Treatment of Calcinosis

Condition: Systemic Sclerosis (SSc) · Dermatomyositis · Mixed Connective Tissue Disease (MCTD)  ·  Sponsor: Robyn T. Domsic, MD, MPH

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The specific objective of this study is to perform a small, open-label study to assess the safety and efficacy of intralesional, subcutaneous injection of STS on calcinosis symptoms and lesion size in systemic sclerosis (SSc), mixed connective tissue disease (MCTD) and dermatomyositis (DM) patients. Injection will be guided by ultrasound, lesion size assessed by ultrasound, and symptom burden by patient-reported outcome measures.

This description comes directly from the study's public registry record.

Talk to the study team

Maureen M Laffoon, BS  ·  412-648-7874  ·  laffoonm@pitt.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UPMC Arthritis and Autoimmunity CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06672822