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Study identifier: NCT06672237 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 3 Study of NTLA-2001 in ATTRv-PN

Condition: Neuromuscular Disease · Neuromuscular Diseases (NMD) · Neurodegenerative Disease  ·  Sponsor: Intellia Therapeutics

PhasePhase 3
Planned participants60
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This study will be conducted to evaluate the efficacy and safety of a single dose of nexiguran ziclumeran (NTLA-2001) compared to placebo in participants with ATTRv-PN.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Manager at Intellia  ·  1-857-285-6200  ·  medicalinformation@intelliatx.com

Always discuss trial participation with your own doctor first.

Locations (14)

Hospital Británico de Buenos AiresBuenos Aires, ArgentinaRecruiting
Hospital Italiano de Buenos Aires (HIBA)Buenos Aires, ArgentinaRecruiting
Hospital El CruceSan Juan Bautista, ArgentinaRecruiting
Hospital das Clinicas da Universidade Estadual de Campinas (UNICAMP)Campinas, BrazilRecruiting
HCFMRP - Hospital das Clinicas da Faculdade de Medicina de Ribeirao PretoRibeirão Preto, BrazilRecruiting
Instituto de Educacao, Pesquisa e Gestao em SaudeRio de Janeiro, BrazilRecruiting
PSEG Centro de Pesquisa Clinica S.A.São Paulo, BrazilRecruiting
National Institute of Medical Sciences and Nutrition - Salvador Zubiran (INCMNSZ)Tlalpan, MexicoRecruiting
National University HospitalSingapore, SingaporeRecruiting
Singapore General HospitalSingapore, SingaporeRecruiting
National Taiwan University HospitalTaipei, TaiwanActive Not Recruiting
Taipei Veterans General HospitalTaipei, TaiwanActive Not Recruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06672237