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Study identifier: NCT06667076 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Condition: Carcinoma, Non-Small-Cell Lung  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 2
Planned participants480
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary purpose of the study is to assess how well amivantamab in combination with lazertinib or in combination with chemotherapy works (antitumor activity) in participants with epidermal growth factor receptor mutated (EGFRm) non-small cell lung cancer (NSCLC; that is one of the major types of lung cancer).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (202)

Southern Cancer Center, PCDaphne, Alabama, United StatesRecruiting
Clearview Cancer InstituteHuntsville, Alabama, United StatesRecruiting
City of Hope PhoenixGoodyear, Arizona, United StatesRecruiting
The Oncology Institute of Hope and InnovationCerritos, California, United StatesRecruiting
City of Hope CoronaCorona, California, United StatesRecruiting
City of HopeDuarte, California, United StatesRecruiting
Providence Medical FoundationFullerton, California, United StatesRecruiting
Oncology Physicians Network HealthcareGlendale, California, United StatesCompleted
Los Angeles Cancer NetworkGlendale, California, United StatesRecruiting
Glendale Adventist Medical CenterGlendale, California, United StatesRecruiting
Marin Cancer CenterGreenbrae, California, United StatesRecruiting
City of Hope SeacliffHuntington Beach, California, United StatesRecruiting

+ 190 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06667076