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Study identifier: NCT06665971 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE)

Condition: Eosinophilic Esophagitis (EoE)  ·  Sponsor: University of California, San Diego

PhasePhase 4
Planned participants30
Who can joinAll sexes, 22 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to research Dupilumab, an FDA approved medication in treating patients diagnosed with Eosinophilic esophagitis (EoE). The drug works by controlling allergic inflammation of the esophagus. The esophagus is a food pipe that transfers food from the mouth into the stomach. Participants with EoE have dysfunction of the muscle of the esophagus (impaired peristalsis) that is not favorable for the transport function. Main question this study aims to answer is: Whether Dupilumab helps improve muscle activity of the esophagus in participants with EOE? Participants will: Take Dupilumab every week for 12 weeks. Visit the clinic before and after starting the medication. Keep a diary of symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Anant Gupta, MBBS  ·  314-685-9214  ·  ucsdgimotility@gmail.com

Ravinder Mittal, MD  ·  858-534-3328  ·  rmittal@health.ucsd.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California San Diego (UCSD) Health Medical centerLa Jolla, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06665971