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Study identifier: NCT06664996 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sintilimab Combined SBRT As Neoadjuvant Therapy for Resectable HCC with PVTT

Condition: Hepatocellular Carcinoma (HCC)  ·  Sponsor: West China Hospital

PhasePhase 2
Planned participants33
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this single-arm, prospective clinical trial is to evaluate the safety and efficacy of neoadjuvant therapy combining sintilimab with stereotactic body radiation therapy (SBRT) in patients with resectable hepatocellular carcinoma (HCC) with branch portal vein tumor thrombus. The main questions it aims to answer are: 1. Is the combination of sintilimab and SBRT safe as neoadjuvant therapy? 2. How effective is this combination in treating resectable HCC with branch PVTT? Participants will be given a combination treatment of sintilimab and SBRT. Researchers will monitor their health conditions to assess the safety and effectiveness of this treatment protocol.

This description comes directly from the study's public registry record.

Talk to the study team

Yi Yang  ·  +8618328699953  ·  yy_devin@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

West China HospitalChengdu, Sichuan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06664996