Condition: Acute Ischemic Stroke · Sponsor: Capital Medical University
The goal of this clinical trial is to learn whether chlorpromazine and promethazine（C+P）is safe in Acute Ischemic Stroke（AIS) patients and determine the maximum dosage. It will also evaluate the preliminary efficacy of C+P in AIS. The main questions it aims to answer are: What is the optimal dosage of C+P that is safe without causing adverse effects in AIS patients? What is the optimal dosage of C+P that potentially works to treat AIS? Researchers will compare C+P with placebo (saline solution without C+P) to see if C+P is safe and effective in treating Acute Ischemic Stroke. Participants will: Receive C+P or placebo at the same time as endovascular thrombectomy begins. Patients will be observed for 72 hours to see if there were any adverse effects related to C+P. Infarct volumes will be evaluated using Computed Tomography. Functional outcomes will be assessed at 90 days.
This description comes directly from the study's public registry record.
Xunming Ji, Doctor · +86 13911077166 · Jixm@ccmu.edu.cn
Hao Wang, Doctor · +86 13518690201 · neurology_hao@163.com
Always discuss trial participation with your own doctor first.
| Linyi People's Hospital | Linyi, Shandong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06663631