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Study identifier: NCT06663319 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Condition: Colorectal Neoplasms · Gastrointestinal Neoplasms  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 1
Planned participants260
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine the putative recommended phase 2 dose(s) (RP2Ds) and best way to take (optimal route of administration) JNJ-89402638 and to determine the safety of JNJ-89402638 at the RP2D(s) in participants with metastatic colorectal cancer (mCRC) and metastatic gastric cancer (mGAC) and to determine the safety and tolerability of JNJ-89402638 in combination with bevacizumab or biosimilar with or without chemotherapy in participants with mCRC.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (11)

University of Colorado Denver Anschultz Medical CampusAurora, Colorado, United StatesRecruiting
Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Community Health NetworkIndianapolis, Indiana, United StatesRecruiting
Start MidwestGrand Rapids, Michigan, United StatesRecruiting
Swedish Cancer InstituteSeattle, Washington, United StatesRecruiting
Severance Hospital Yonsei University Health SystemSeoul, South KoreaRecruiting
Asan Medical CenterSeoul, South KoreaRecruiting
Hosp Univ Vall D HebronBarcelona, SpainRecruiting
Hosp Univ Fund Jimenez DiazMadrid, SpainRecruiting
Hosp. Univ. 12 de OctubreMadrid, SpainRecruiting
Hosp Univ Hm SanchinarroMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06663319