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Study identifier: NCT06663098 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).

Condition: Extensive Stage Small Cell Lung Cancer (ES-SCLC)  ·  Sponsor: Gruppo Oncologico Italiano di Ricerca Clinica

PhasePhase 2
Planned participants142
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if a combination of atezolizumab and standard chemotherapy works to treat sensitive Extensive-stage Small Cell Lung Cancer, progressing after first-line of treatment. The main questions it aims to answer are: * Does combination of atezolizumab and standard chemotherapy increase overall survival? * What medical problems do participants have when taking combination of atezolizumab and standard chemotherapy? Participants will: * take atezolizumab and standard chemotherapy every 3 weeks for 4 cycles and than atezolizumab every 3 weeks up to 18 cycles. * visit the clinic once every 3 weeks for checkups and tests * perform Radiological assessments after 6 weeks and then every 12 weeks to determine response to treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Andrea Ardizzoni, MD  ·  0039-051-2142206  ·  andrea.ardizzoni@aosp-bo.itt

Giuseppe Lamberti, MD  ·  0039-051-2143067  ·  giuseppe.lamberti8@unibo.it

Always discuss trial participation with your own doctor first.

Locations (25)

Centro di Riferimento Oncologico di Aviano (CRO) IRCCSAviano (PN), ItalyNot Yet Recruiting
IRCCS Istituto Tumori "Giovanni Paolo II"Bari, ItalyNot Yet Recruiting
IRCCS Azienda Ospedaliero_Universitaria di BolognaBologna, ItalyRecruiting
UOC Medicina OncologicaCarpi, ItalyNot Yet Recruiting
ASST CremonaCremona, ItalyNot Yet Recruiting
Azienda Ospedaliera S. Croce e Carle di CuneoCuneo, ItalyNot Yet Recruiting
AOU CareggiFlorence, ItalyNot Yet Recruiting
Azienda USL Toscana nord-ovest Ospedale VersiliaLido di Camaiore, ItalyRecruiting
Azienda USL Toscana Nord Ovest - Ospedale San LucaLucca, ItalyNot Yet Recruiting
Istituto Scientifico Romagnolo per lo studio e la cura dei Tumori (IRST) "Dino Amadori"Meldola (FC), ItalyNot Yet Recruiting
IRCCS Ospedale San RaffaeleMilan, ItalyNot Yet Recruiting
AOU Policlinico di ModenaModena, ItalyNot Yet Recruiting

+ 13 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT06663098