Condition: Colorectal Neoplasms · Sponsor: Janssen Research & Development, LLC
The purpose of this study is to compare how long the participants are disease-free (progression-free survival) when treated with amivantamab and chemotherapy with 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, oxaliplatin (mFOLFOX6) or 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, and irinotecan hydrochloride (FOLFIRI) versus cetuximab and mFOLFOX6 or FOLFIRI in adult participants with Kirsten rat sarcoma viral oncogene homolog (KRAS)/ Neuroblastoma RAS viral oncogene homolog (NRAS) and v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) wild type (WT) unresectable or metastatic left-sided colorectal cancer.
This description comes directly from the study's public registry record.
Study Contact · 844-434-4210 · Participate-In-This-Study1@its.jnj.com
Always discuss trial participation with your own doctor first.
| Banner MD Anderson Cancer Center | Gilbert, Arizona, United States | Recruiting |
| St. Bernard's Medical Center | Jonesboro, Arkansas, United States | Recruiting |
| Highlands Oncology Group | Springdale, Arkansas, United States | Recruiting |
| CBCC Global Research | Bakersfield, California, United States | Recruiting |
| Los Angeles Cancer Network | Glendale, California, United States | Recruiting |
| Cancer and Blood Specialty Clinic | Los Alamitos, California, United States | Recruiting |
| USC Norris Comprehensive Cancer Center | Los Angeles, California, United States | Recruiting |
| UCLA | Santa Monica, California, United States | Recruiting |
| Providence Medical Foundation | Santa Rosa, California, United States | Recruiting |
| Torrance Memorial Physicians Network | Torrance, California, United States | Recruiting |
| Rocky Mountain Cancer Centers | Denver, Colorado, United States | Recruiting |
| Yale University School Of Medicine | New Haven, Connecticut, United States | Recruiting |
+ 225 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06662786