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Study identifier: NCT06662006 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Nal-IRI/5-FU/LV Chemotherapy Combined With PD-L1 Inhibitor and Multi-target Anti-angiogenic Small Molecule±SBRT as Second-line Therapy in Metastatic Pancreatic Cancer Patients

Condition: Advanced Metastatic Pancreatic Cancer  ·  Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

PhasePhase 2
Planned participants56
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a single-arm, multi-center, multi-cohort, prospective clinical study initiated by the investigator. The indication of this study is: patients with advanced metastatic pancreatic cancer who have progressed after first-line chemotherapy. Eligible patients will be assigned to liposomal irinotecan (nal-IRI) plus 5-fluorouracil (5-FU)/leucovorin (LV) (nal-IRI/5-FU/LV) combined with benmelstobart and anlotinib ± SBRT. The total sample size for this study is expected to be 56 subjects.

This description comes directly from the study's public registry record.

Talk to the study team

Juan Du, M.D. Ph.D  ·  +86-025-83106666  ·  dujunglyy@163.com

DU  ·  dujunglyy@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolNanjing, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06662006