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Study identifier: NCT06660693 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparison of Medical RESCUE Strategies for Patients With Steroid-refractory Acute Severe Ulcerative Colitis

Condition: Colitis, Ulcerative  ·  Sponsor: McMaster University

PhasePhase 3
Planned participants134
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersNo

About this study

This study aims to examine patients with acute severe UC who are refractory to intravenous corticosteroids and determine whether a strategy of using upadacitinib first followed by infliximab in upadacitinib non-responders is non-inferior to conventional management with infliximab only.

This description comes directly from the study's public registry record.

Talk to the study team

Neeraj Narula  ·  905-521-2011  ·  neeraj.narula@medportal.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Hamilton Health SciencesHamilton, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06660693