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Study identifier: NCT06660368 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

Condition: Relapsed or Refractory Acute Myeloid Leukemia (AML)  ·  Sponsor: H. Lee Moffitt Cancer Center and Research Institute

PhasePhase 2
Planned participants52
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This multicenter, open-label phase II study combines CLAG-based therapy with or without venetoclax in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) in order to improve measurable residual disease (MRD) clearance and event-free survival. Investigators hypothesize that the addition of venetoclax to CLAG-M in patients with relapsed or refractory AML is safe, and superior to CLAG-M alone in improving patient outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Quan Lovette  ·  813-745-4194  ·  quan.lovette@moffitt.org

Always discuss trial participation with your own doctor first.

Locations (2)

Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06660368