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Study identifier: NCT06660277 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DIALysis With EXpanded Solute Removal

Condition: Chronic Kidney Disease Requiring Hemodialysis · End-Stage Kidney Disease (ESKD) · Chronic Kidney Disease Requiring Chronic Dialysis  ·  Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

PhaseNA
Planned participants4800
Who can joinAll sexes, 45 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the health effects of expanded hemodialysis in patients receiving hemodialysis. The main question it aims to answer is: 1\) Does expanded hemodialysis reduce the risk of death from any cause? Researchers will compare expanded hemodialysis to conventional hemodialysis (the treatment currently used for the majority of patients receiving hemodialysis) to see if expanded hemodialysis works to improve patient outcomes. Participants will continue to receive their regularly scheduled hemodialysis treatments using either a super high-flux/expanded dialysis filter or a high-flux/conventional dialysis filter. All other aspects of treatments remain the same. No additional tests or visits are required. Data will be obtained using administrative healthcare databases and medical record review (at a subset of participating locations).

This description comes directly from the study's public registry record.

Talk to the study team

Pavel S Roshanov, MD MSc FRCPC  ·  519-663-3350  ·  pavel.roshanov@lhsc.on.ca

Central Research Coordinator  ·  fixdialysis@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (1)

London Health Sciences CentreLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06660277