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Study identifier: NCT06657911 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Size Up Bicuspid With the LIra MEthod: the SUBLIME Study

Condition: Bicuspid Aortic Valve (BAV)  ·  Sponsor: IRCCS San Raffaele

PhaseN/A
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Transcatheter aortic valve replacement (TAVR) outcomes in patients with raphe-type bicuspid aortic valve (BAV) are still suboptimal for the non negligible rate of stroke and permanent pacemaker implantation. There is still lack of consensus on the optimal sizing method for prosthesis selection in BAV patients. The objective of the present study is to evaluate the efficacy and safety of the LIRA sizing method in raphe-type BAV patients undergoing TAVR.

This description comes directly from the study's public registry record.

Talk to the study team

Prof. Matteo Montorfano, MD  ·  0039/02/26437331  ·  montorfano.matteo@hsr.it

Barbara Bellini, MD  ·  0039/02/26437331  ·  bellini.barbara@hsr.it

Always discuss trial participation with your own doctor first.

Locations (5)

Fondazione PoliambulanzaBrescia, Italy, ItalyRecruiting
Spedali CiviliBrescia, Italy, ItalyRecruiting
Ospedale San DonatoMilan, Italy, ItalyRecruiting
San Camillo HospitalRoma, Italy, ItalyRecruiting
Luzerner KantonsspitalLucerne, Switzerland, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06657911